ANTXR1, Goat, Polyclonal Antibody, Abnova™

Catalog No.	Quantity
89-132-590	100 μg

Catalog No. 89-132-590 Supplier Abnova Corporation Supplier No. PAB6677

Description

Goat polyclonal antibody raised against synthetic peptide of ANTXR1.

This gene encodes a type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer. The encoded protein has been shown to also be a docking protein or receptor for Bacillus anthracis toxin, the causative agent of the disease, anthrax. The binding of the protective antigen (PA) component, of the tripartite anthrax toxin, to this receptor protein mediates delivery of toxin components to the cytosol of cells. Once inside the cell, the other two components of anthrax toxin, edema factor (EF) and lethal factor (LF) disrupt normal cellular processes. Three alternatively spliced variants that encode different protein isoforms have been described. [provided by RefSeq

Sequence: C-RAPPPSRPPPRPSV

Specifications

• Antigen: ANTXR1
• Applications: ELISA, Western Blot
• Classification: Polyclonal
• Concentration: 0.5 mg/mL
• Conjugate: Unconjugated
• Description: Goat polyclonal antibody raised against synthetic peptide of ANTXR1.
• Dilution: ELISA (1:64000) Western Blot (0.2-1 ug/mL) The optimal working dilution should be determined by the end user.
• Formulation: In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
• Gene: ANTXR1
• Gene Accession No.: NP_115584
• Gene Alias: ATR/FLJ10601/FLJ11298/FLJ21776/TEM8
• Gene Symbols: ANTXR1
• Host Species: Goat
• Immunogen: A synthetic peptide corresponding to human ANTXR1.
• Purification Method: Antigen affinity purification
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 84168
• Test Specificity: This antibody is expected to recognize variant 1 (NP_115584) only.
• Target Species: Human
• Content And Storage: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid

For Research Use Only