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APBB1, Goat, Polyclonal Antibody, Abnova™

Catalog No. 89132939 Shop All Abnova Corporation Products
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89-132-939 100 μg
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Catalog No. 89-132-939 Supplier Abnova Corporation Supplier No. PAB7086
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Goat polyclonal antibody raised against synthetic peptide of APBB1.

The protein encoded by this gene is a member of the Fe65 protein family. It is an adaptor protein localized in the nucleus. It interacts with the Alzheimer's disease amyloid precursor protein (APP), transcription factor CP2/LSF/LBP1 and the low-density lipoprotein receptor-related protein. APP functions as a cytosolic anchoring site that can prevent the gene product's nuclear translocation. This encoded protein could play an important role in the pathogenesis of Alzheimer's disease. It is thought to regulate transcription. Also it is observed to block cell cycle progression by downregulating thymidylate synthase expression. Multiple alternatively spliced transcript variants have been described for this gene but some of their full length sequence is not known. [provided by RefSeq]

Sequence: C-GSLKPKRLGAHTP

Specifications

Antigen APBB1
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Description Goat polyclonal antibody raised against synthetic peptide of APBB1.
Dilution ELISA (1:128000) Western Blot (0.1-0.3 ug/mL) The optimal working dilution should be determined by the end user.
Formulation In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Gene APBB1
Gene Accession No. NP_001155.1;NP_663722.1
Gene Alias FE65/MGC:9072/RIR
Gene Symbols APBB1
Host Species Goat
Immunogen A synthetic peptide corresponding to human APBB1.
Purification Method Antigen affinity purification
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 322
Test Specificity This antibody is expected to recognize both reported isoforms (NP_001155.1 and NP_663722.1).
Target Species Human, Mouse
Content And Storage Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
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For Research Use Only

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