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APEX1, Goat, Polyclonal Antibody, Abnova™

Catalog No. 89132166 Shop All Abnova Corporation Products
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89-132-166 100 μg
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Catalog No. 89-132-166 Supplier Abnova Corporation Supplier No. PAB6125
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Description

Goat polyclonal antibody raised against synthetic peptide of APEX1.

Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. This gene encodes the major AP endonuclease in human cells. Splice variants have been found for this gene; all encode the same protein. [provided by RefSeq]

Sequence: PKRGKKGAVAEDGD-C

Specifications

Antigen APEX1
Applications ELISA, Immunohistochemistry (PFA fixed), Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Description Goat polyclonal antibody raised against synthetic peptide of APEX1.
Dilution ELISA (1:16000) Western Blot (0.1-0.3 ug/mL) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (4-6 ug/mL) The optimal working dilution should be determined by the end user.
Formulation In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Gene APEX1
Gene Accession No. NP_001632.2;NP_542379.1;NP_542380.1
Gene Alias APE/APE-1/APE1/APEN/APEX/APX/HAP1/REF-1/REF1
Gene Symbols APEX1
Host Species Goat
Immunogen A synthetic peptide corresponding to N-terminus of human APEX1.
Purification Method Antigen affinity purification
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 328
Test Specificity This antibody is expected to recognize NP_001632.2, NP_542379.1 and NP_542380.1 are varients that represent the same protein.
Target Species Human
Content And Storage Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
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For Research Use Only

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