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APOE Goat anti-Human, Polyclonal Antibody, Abnova™

Catalog No. 89134537 Shop All Abnova Corporation Products
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500 μg
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Catalog No. Quantity
89-134-537 500 μg
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Catalog No. 89-134-537 Supplier Abnova Corporation Supplier No. PAB9972
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Description

Goat polyclonal antibody raised against native APOE.

Chylomicron remnants and very low density lipoprotein (VLDL) remnants are rapidly removed from the circulation by receptor-mediated endocytosis in the liver. Apolipoprotein E, a main apoprotein of the chylomicron, binds to a specific receptor on liver cells and peripheral cells. ApoE is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. The APOE gene is mapped to chromosome 19 in a cluster with APOC1 and APOC2. Defects in apolipoprotein E result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants. [provided by RefSeq

Specifications

Antigen APOE
Applications ELISA, Immunohistochemistry, Immunoprecipitation, Western Blot
Classification Polyclonal
Conjugate Unconjugated
Description Goat polyclonal antibody raised against native APOE.
Dilution ELISA (1:4000-1:8000)
Western Blot (1:500-1:2000)
Immunohistochemistry (1:50-1:200) The optimal working dilution should be determined by the end user.
Formulation In 100mM Na2B4O7, 75mM NaCl, 5mM EDTA, pH 8.0 (0.01% sodium azide)
Gene APOE
Gene Alias AD2/LPG/MGC1571/apoprotein
Gene Symbols APOE
Host Species Goat
Immunogen Native purified human APOE.
Quantity 500 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 348
Test Specificity This antibody reacts with human apoLipoprotein E and has negligible cross-reactivity with Type A-1 A-II, B, C-I, C-II, C-III and J apoLipoproteins. Non-specific cross-reaction of anti-apoLipoprotein antibodies with other human serum proteins is negligible.
Target Species Human
Content And Storage Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
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For Research Use Only

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