ARTN, Goat, Polyclonal Antibody, Abnova™

Goat polyclonal antibody raised against synthetic peptide of ARTN.

Supplier:  Abnova Corporation PAB18977

Catalog No. 89-120-529

Description

The protein encoded by this gene is a member of the glial cell line-derived neurotophic factor (GDNF) family of ligands which are a group of ligands within the TGF-beta superfamily of signaling molecules. GDNFs are unique in having neurotrophic properties and have potential use for gene therapy in neurodegenerative disease. Artemin has been shown in culture to support the survival of a number of peripheral neuron populations and at least one population of dopaminergic CNS neurons. Its role in the PNS and CNS is further substantiated by its expression pattern in the proximity of these neurons. This protein is a ligand for the RET receptor and uses GFR-alpha 3 as a coreceptor. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq

Sequence: C-NSTWRTVDRLS

Specifications

• Antigen: ARTN
• Classification: Polyclonal
• Conjugate: Unconjugated
• Dilution: ELISA (1:8000) Western Blot (0.1-0.3 ug/mL) The optimal working dilution should be determined by the end user.
• Gene: ARTN
• Gene Alias: ENOVIN/EVN/NBN
• Host Species: Goat
• Purification Method: Antigen affinity purification
• Regulatory Status: RUO
• Gene ID (Entrez): 9048
• Target Species: Human
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 0.5 mg/mL
• Description: Goat polyclonal antibody raised against synthetic peptide of ARTN.
• Formulation: In 0.5mg/mL in Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
• Gene Accession No.: NP_476431.2
• Gene Symbols: ARTN
• Immunogen: A synthetic peptide corresponding to amino acids at internal region of human ARTN.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Test Specificity: This antibody is expected to recognize all reported isoforms (NP_003967.2; NP_476501.1; NP_476431.2). Reported variants represent identical protein: NP_476431.2, NP_001129687.1 Reported variants represent identical protein: NP_003967.2, NP_476432.2
• Content And Storage: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.

For Research Use Only