ATP2B1, Goat, Polyclonal Antibody, Abnova™

Goat polyclonal antibody raised against synthetic peptide of ATP2B1.

Supplier:  Abnova Corporation PAB24566

Catalog No. 89-126-283

Description

The protein encoded by this gene belongs to the family of P-type primary ion transport ATPases characterized by the formation of an aspartyl phosphate intermediate during the reaction cycle. These enzymes remove bivalent calcium ions from eukaryotic cells against very large concentration gradients and play a critical role in intracellular calcium homeostasis. The mammalian plasma membrane calcium ATPase isoforms are encoded by at least four separate genes and the diversity of these enzymes is further increased by alternative splicing of transcripts. The expression of different isoforms and splice variants is regulated in a developmental, tissue- and cell type-specific manner, suggesting that these pumps are functionally adapted to the physiological needs of particular cells and tissues. This gene encodes the plasma membrane calcium ATPase isoform 1. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq

Sequence: C-KQDGAIENRNKAKAQD

Specifications

• Antigen: ATP2B1
• Classification: Polyclonal
• Description: Goat polyclonal antibody raised against synthetic peptide of ATP2B1.
• Formulation: In 0.5mg/mL Tris saline, pH 7.3 (0.02% sodium azide, 0.5% BSA)
• Gene Accession No.: NP_001001323.1;NP_001673.2
• Gene Symbols: ATP2B1
• Immunogen: A synthetic peptide corresponding to amino acids 312-327 at internal region of human ATP2B1.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Test Specificity: This antibody is expected to recognize both reported isoforms (NP_001001323.1; NP_001673.2).
• Content And Storage: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.

• Applications: ELISA, Western Blot
• Conjugate: Unconjugated
• Dilution: ELISA (1:64000) Western Blot (0.03-0.1 ug/mL) The optimal working dilution should be determined by the end user.
• Gene: ATP2B1
• Gene Alias: PMCA1/PMCA1kb
• Host Species: Goat
• Purification Method: Antigen affinity purification
• Regulatory Status: RUO
• Gene ID (Entrez): 490
• Target Species: Human
• Form: Liquid

For Research Use Only