AXIN1, Goat, Polyclonal Antibody, Abnova™

Catalog No.	Quantity
89-132-179	100 μg

Catalog No. 89-132-179 Supplier Abnova Corporation Supplier No. PAB6140

Description

Goat polyclonal antibody raised against synthetic peptide of AXIN1.

This gene encodes a cytoplasmic protein which contains a regulation of G-protein signaling (RGS) domain and a dishevelled and axin (DIX) domain. The encoded protein interacts with adenomatosis polyposis coli, catenin (cadherin-associated protein), beta 1, 88kDa, glycogen synthase kinase 3 beta, protein phosphate 2, and itself. This protein functions as a negative regulator of the wingless-type MMTV integration site family, member 1 (WNT) signaling pathway and can induce apoptosis. The crystal structure of a portion of this protein, alone and in a complex with other proteins, has been resolved. Mutations in this gene have been associated with hepatocellular carcinoma, hepatoblastomas, ovarian endometriod adenocarcinomas, and medullablastomas. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq

Sequence: C-FEEKIIGKVEKVD

Specifications

• Antigen: AXIN1
• Applications: ELISA, Immunohistochemistry (PFA fixed)
• Classification: Polyclonal
• Concentration: 0.5 mg/mL
• Conjugate: Unconjugated
• Description: Goat polyclonal antibody raised against synthetic peptide of AXIN1.
• Dilution: ELISA (1:128000) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (3-5 ug/mL) The optimal working dilution should be determined by the end user.
• Formulation: In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
• Gene: AXIN1
• Gene Accession No.: NP_003493.1;NP_851393.1
• Gene Alias: AXIN/MGC52315
• Gene Symbols: AXIN1
• Host Species: Goat
• Immunogen: A synthetic peptide corresponding to human AXIN1.
• Purification Method: Antigen affinity purification
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 8312
• Test Specificity: This antibody is expected to recognize both reported isoforms.
• Target Species: Human
• Content And Storage: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid

For Research Use Only