BAG4, Goat, Polyclonal Antibody, Abnova™

Catalog No.	Quantity
89-121-227	100 μg

Catalog No. 89-121-227 Supplier Abnova Corporation Supplier No. PAB19700

Description

Goat polyclonal antibody raised against synthetic peptide of BAG4.

The protein encoded by this gene is a member of the BAG1-related protein family. BAG1 is an anti-apoptotic protein that functions through interactions with a variety of cell apoptosis and growth related proteins including BCL-2, Raf-protein kinase, steroid hormone receptors, growth factor receptors and members of the heat shock protein 70kDa family. This protein contains a BAG domain near the C-terminus, which could bind and inhibit the chaperone activity of Hsc70/Hsp70. This protein was found to be associated with the death domain of tumor necrosis factor receptor type 1 (TNF-R1) and death receptor-3 (DR3), and thereby negatively regulates downstream cell death signaling. The regulatory role of this protein in cell death was demonstrated in epithelial cells which undergo apoptosis while integrin mediated matrix contacts are lost. [provided by RefSeq

Sequence: C-GNATSDHPNNQDQSS

Specifications

• Antigen: BAG4
• Applications: ELISA, Western Blot
• Classification: Polyclonal
• Conjugate: Unconjugated
• Description: Goat polyclonal antibody raised against synthetic peptide of BAG4.
• Dilution: ELISA (1:8000) Western Blot (0.3-1 ug/mL) The optimal working dilution should be determined by the end user.
• Formulation: In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
• Gene: BAG4
• Gene Accession No.: NP_004865.1
• Gene Alias: BAG-4/SODD
• Gene Symbols: BAG4
• Host Species: Goat
• Immunogen: A synthetic peptide corresponding to internal region of human BAG4.
• Purification Method: Antigen affinity purification
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 9530
• Target Species: Human
• Content And Storage: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid

For Research Use Only