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BBS4 Goat anti-Human, Polyclonal Antibody, Abnova™
Goat polyclonal antibody raised against synthetic peptide of BBS4.
Manufacturer: Abnova Corporation PAB18993
Description
This gene is a member of the Bardet-Biedl syndrome (BBS) gene family. Bardet-Biedl syndrome is an autosomal recessive disorder characterized by severe pigmentary retinopathy, obesity, polydactyly, renal malformation and mental retardation. The proteins encoded by BBS gene family members are structurally diverse. The similar phenotypes exhibited by mutations in BBS gene family members are likely due to the protein's shared roles in cilia formation and function. Many BBS proteins localize to the basal bodies, ciliary axonemes, and pericentriolar regions of cells. BBS proteins may also be involved in intracellular trafficking via microtubule-related transport. The protein encoded by this gene has sequence similarity to O-linked N-acetylglucosamine (O-GlcNAc) transferases in plants and archaebacteria and in human forms a multi-protein ''BBSome'' complex with six other BBS proteins. Alternative splice variants have been described but their predicted protein products have not been experimentally verified
Sequence: C-NEAAKLNQKDWEISHSpecifications
BBS4 | |
Polyclonal | |
Unconjugated | |
ELISA (1:32000) Western Blot (1-3 ug/mL) The optimal working dilution should be determined by the end user. | |
BBS4 | |
BBS4 | |
A synthetic peptide corresponding to amino acids at internal region of human BBS4. | |
100 μg | |
Primary | |
Human |
ELISA, Western Blot | |
0.5 mg/mL | |
Goat polyclonal antibody raised against synthetic peptide of BBS4. | |
In 0.5mg/mL in Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide) | |
NP_149017.2 | |
Goat | |
Antigen affinity purification | |
RUO | |
585 | |
Liquid |
Safety and Handling
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For Research Use Only