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BBS4 Goat anti-Human, Polyclonal Antibody, Abnova™

Goat polyclonal antibody raised against synthetic peptide of BBS4.

Manufacturer:  Abnova Corporation PAB18993

Catalog No. 89-120-547


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Description

Description

This gene is a member of the Bardet-Biedl syndrome (BBS) gene family. Bardet-Biedl syndrome is an autosomal recessive disorder characterized by severe pigmentary retinopathy, obesity, polydactyly, renal malformation and mental retardation. The proteins encoded by BBS gene family members are structurally diverse. The similar phenotypes exhibited by mutations in BBS gene family members are likely due to the protein's shared roles in cilia formation and function. Many BBS proteins localize to the basal bodies, ciliary axonemes, and pericentriolar regions of cells. BBS proteins may also be involved in intracellular trafficking via microtubule-related transport. The protein encoded by this gene has sequence similarity to O-linked N-acetylglucosamine (O-GlcNAc) transferases in plants and archaebacteria and in human forms a multi-protein ''BBSome'' complex with six other BBS proteins. Alternative splice variants have been described but their predicted protein products have not been experimentally verified

Sequence: C-NEAAKLNQKDWEISH
Specifications

Specifications

BBS4
0.5 mg/mL
Goat polyclonal antibody raised against synthetic peptide of BBS4.
In 0.5mg/mL in Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
NP_149017.2
BBS4
A synthetic peptide corresponding to amino acids at internal region of human BBS4.
100 ug
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Polyclonal
Human
ELISA, Western Blot
Unconjugated
ELISA (1:32000) Western Blot (1-3 ug/mL) The optimal working dilution should be determined by the end user.
BBS4
Liquid
Goat
Antigen affinity purification
RUO
Primary
585
SDS
Documents
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