CASP3, Goat, Polyclonal Antibody, Abnova™

Catalog No.	Quantity
89-129-097	100 μg

Catalog No. 89-129-097 Supplier Abnova Corporation Supplier No. PAB27586

Description

Goat polyclonal antibody raised against synthetic peptide of CASP3.

This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. Alternative splicing of this gene results in two transcript variants that encode the same protein. [provided by RefSeq]

Sequence: RDVSKEDHSKRS

Specifications

• Antigen: CASP3
• Applications: Western Blot
• Classification: Polyclonal
• Concentration: 0.5 mg/mL
• Conjugate: Unconjugated
• Description: Goat polyclonal antibody raised against synthetic peptide of CASP3.
• Dilution: ELISA (1:32000) Western Blot (1-3ug/ml) The optimal working dilution should be determined by the end user.
• Formulation: In Tris saline, pH 7.3 (0.02% sodium azide, 0.5% BSA)
• Gene: CASP3
• Gene Accession No.: NP_004337.2;NP_116786.1
• Gene Alias: CPP32/CPP32B/SCA-1
• Gene Symbols: CASP3
• Host Species: Goat
• Immunogen: A synthetic peptide corresponding to internal region of human CASP3.
• Purification Method: Affinity Purified
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 836
• Target Species: Canine, Human, Mouse, Rat
• Content And Storage: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.

For Research Use Only