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CD244, Goat, Polyclonal Antibody, Abnova™

Catalog No. 89119468 Shop All Abnova Corporation Products
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100 μg
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89-119-468 100 μg
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Catalog No. 89-119-468 Supplier Abnova Corporation Supplier No. PAB17803
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Goat polyclonal antibody raised against synthetic phosphopeptide of CD244.

Natural killer (NK) cells express both activating and inhibitory cell surface receptors. Inhibitory signaling receptors all possess cytoplasmic immunoreceptor tyrosine-based inhibitory motifs, or ITIMs, whereas the activating receptors lack ITIMs and associate with DAP12 (TYROBP; MIM 604142), which contains an immunoreceptor tyrosine-based activation motif, or ITAM. Killer cell immunoglobulin (Ig)-like receptors, or KIRs (see KIR2DL1; MIM 604936), and other NK cell receptors interact with major histocompatibility complex (MHC) molecules (see MIM 142800). Members of the CD2 (MIM 186990) family adhere to each other instead. The cell surface glycoprotein 2B4 is related to CD2 and is implicated in the regulation of NK- and T-cell function (Boles et al., 1999 [PubMed 10458320]).[supplied by OMIM

Sequence: C-EFLTIpYEDVKD

Specifications

Antigen CD244
Applications ELISA, Immunoprecipitation, Western Blot
Classification Polyclonal
Conjugate Unconjugated
Description Goat polyclonal antibody raised against synthetic phosphopeptide of CD244.
Dilution ELISA (1:64000) Western Blot (1-3 ug/mL) The optimal working dilution should be determined by the end user.
Formulation In 0.5mg/mL Tris saline, pH 7.3 (0.02% sodium azide, 0.5% BSA)
Gene CD244
Gene Accession No. NP_057466.1
Gene Alias 2B4/NAIL/NKR2B4/Nmrk/SLAMF4
Gene Symbols CD244
Host Species Goat
Immunogen Synthetic phosphopeptide corresponding to internal region of residues surrounding Y266 of human CD244.
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 51744
Target Species Human
Content And Storage Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
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For Research Use Only

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