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CDH1, Goat, Polyclonal Antibody, Abnova™

Catalog No. 89126301 Shop All Abnova Corporation Products
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89-126-301 100 μg
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Catalog No. 89-126-301 Supplier Abnova Corporation Supplier No. PAB24584
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Goat polyclonal antibody raised against synthetic peptide of CDH1.

This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function is thought to contribute to progression in cancer by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. Identified transcript variants arise from mutation at consensus splice sites. [provided by RefSeq

Sequence: C-DYKINLKLMDNQNK

Specifications

Antigen CDH1
Applications ELISA, Western Blot
Classification Polyclonal
Conjugate Unconjugated
Description Goat polyclonal antibody raised against synthetic peptide of CDH1.
Dilution ELISA (1:16000) Western Blot (0.3-1 ug/mL) The optimal working dilution should be determined by the end user.
Formulation In 0.5mg/mL Tris saline, pH 7.3 (0.02% sodium azide, 0.5% BSA)
Gene CDH1
Gene Accession No. NP_004351.1
Gene Alias Arc-1/CD324/CDHE/ECAD/LCAM/UVO
Gene Symbols CDH1
Host Species Goat
Immunogen A synthetic peptide corresponding to amino acids 662-675 at internal region of human CDH1.
Purification Method Antigen affinity purification
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 999
Test Specificity The immunizing peptide represents part of the extracellular domain.
Target Species Human
Content And Storage Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
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For Research Use Only

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