CMA1, Goat, Polyclonal Antibody, Abnova™

Catalog No.	Quantity
89-129-096	100 μg

Catalog No. 89-129-096 Supplier Abnova Corporation Supplier No. PAB27585

Description

Goat polyclonal antibody raised against synthetic peptide of CMA1.

This gene product is a chymotryptic serine proteinase that belongs to the peptidase family S1. It is expressed in mast cells and thought to function in the degradation of the extracellular matrix, the regulation of submucosal gland secretion, and the generation of vasoactive peptides. In the heart and blood vessels, this protein, rather than angiotensin converting enzyme, is largely responsible for converting angiotensin I to the vasoactive peptide angiotensin II. Angiotensin II has been implicated in blood pressure control and in the pathogenesis of hypertension, cardiac hypertrophy, and heart failure. Thus, this gene product is a target for cardiovascular disease therapies. This gene maps to 14q11.2 in a cluster of genes encoding other proteases. [provided by RefSeq

Sequence: QFRHPKYNTSTLHHD

Specifications

• Antigen: CMA1
• Applications: Western Blot
• Classification: Polyclonal
• Concentration: 0.5 mg/mL
• Conjugate: Unconjugated
• Description: Goat polyclonal antibody raised against synthetic peptide of CMA1.
• Dilution: ELISA (1:32000) Western Blot (0.5-2ug/ml) The optimal working dilution should be determined by the end user.
• Formulation: In Tris saline, pH 7.3 (0.02% sodium azide, 0.5% BSA)
• Gene: CMA1
• Gene Accession No.: NP_001827.1
• Gene Alias: CYH/MCT1/MGC119890/MGC119891/chymase
• Gene Symbols: CMA1
• Host Species: Goat
• Immunogen: A synthetic peptide corresponding to internal region of human CMA1.
• Purification Method: Affinity Purified
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 1215
• Target Species: Human
• Content And Storage: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.

For Research Use Only