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Description
This gene encodes one of the two alpha chains of type XI collagen, a minor fibrillar collagen. Type XI collagen is a heterotrimer but the third alpha chain is a post-translationally modified alpha 1 type II chain. Mutations in this gene are associated with type II Stickler syndrome and with Marshall syndrome. A single-nucleotide polymorphism in this gene is also associated with susceptibility to lumbar disc herniation. Three transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq
Specifications
Specifications
| Antigen | COL11A1 |
| Applications | ELISA |
| Classification | Polyclonal |
| Conjugate | Unconjugated |
| Description | collagen, type XI, alpha 1 |
| Formulation | In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide) |
| Gene | COL11A1 |
| Gene Accession No. | NP_001845.3;NP_542196.2;NP_542197.2 |
| Gene Alias | CO11A1, COLL6, STL2 |
| Gene Symbols | COL11A1 |
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