CYB5R3, Goat, Polyclonal Antibody, Abnova™

Catalog No.	Quantity
89-121-174	100 μg

Catalog No. 89-121-174 Supplier Abnova Corporation Supplier No. PAB19649

Description

Goat polyclonal antibody raised against synthetic peptide of CYB5R3.

This gene encodes cytochrome b5 reductase, which includes a membrane-bound form in somatic cells (anchored in the endoplasmic reticulum, mitochondrial and other membranes) and a soluble form in erythrocytes. The membrane-bound form exists mainly on the cytoplasmic side of the endoplasmic reticulum and functions in desaturation and elongation of fatty acids, in cholesterol biosynthesis, and in drug metabolism. The erythrocyte form is located in a soluble fraction of circulating erythrocytes and is involved in methemoglobin reduction. The membrane-bound form has both membrane-binding and catalytic domains, while the soluble form has only the catalytic domain. These two forms are resulted from alternative splicing of the gene. Mutations in this gene cause methemoglobinemias. [provided by RefSeq

Sequence: CLPNLDHVGHPTER

Specifications

• Antigen: CYB5R3
• Applications: ELISA, Immunohistochemistry (PFA fixed), Western Blot
• Classification: Polyclonal
• Conjugate: Unconjugated
• Description: Goat polyclonal antibody raised against synthetic peptide of CYB5R3.
• Dilution: Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)(3-5 ug/mL) ELISA (1:32000) Western Blot (0.01-0.03 ug/mL) The optimal working dilution should be determined by the end user.
• Formulation: In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
• Gene: CYB5R3
• Gene Accession No.: NP_000389.1;NP_001123291.1;NP_001165131.1
• Gene Alias: B5R/DIA1
• Gene Symbols: CYB5R3
• Host Species: Goat
• Immunogen: A synthetic peptide corresponding to C-terminus of human CYB5R3.
• Purification Method: Antigen affinity purification
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 1727
• Test Specificity: This antibody is expected to recognize all three reported isoforms (NP_000389.1; NP_001123291.1; NP_001165131.1).
• Target Species: Human
• Content And Storage: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid

For Research Use Only