CYP17A1, Goat, Polyclonal Antibody, Abnova™

Catalog No.	Quantity
89-132-876	100 μg

Catalog No. 89-132-876 Supplier Abnova Corporation Supplier No. PAB7014

Description

Goat polyclonal antibody raised against synthetic peptide of CYP17A1.

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. It has both 17alpha-hydroxylase and 17,20-lyase activities and is a key enzyme in the steroidogenic pathway that produces progestins, mineralocorticoids, glucocorticoids, androgens, and estrogens. Mutations in this gene are associated with isolated steroid-17 alpha-hydroxylase deficiency, 17-alpha-hydroxylase/17,20-lyase deficiency, pseudohermaphroditism, and adrenal hyperplasia. [provided by RefSeq

Sequence: C-LFKDGDQKLEK

Specifications

• Antigen: CYP17A1
• Applications: ELISA, Immunohistochemistry (PFA fixed), Western Blot
• Classification: Polyclonal
• Concentration: 0.5 mg/mL
• Conjugate: Unconjugated
• Description: Goat polyclonal antibody raised against synthetic peptide of CYP17A1.
• Dilution: ELISA (1:64000) Western Blot (0.1-0.3 ug/mL) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (3-5 ug/mL) The optimal working dilution should be determined by the end user.
• Formulation: In 0.5mg/mL Tris saline, pH 7.3 (0.02% sodium azide, 0.5% BSA)
• Gene: CYP17A1
• Gene Accession No.: NP_000093.1
• Gene Alias: CPT7/CYP17/P450C17/S17AH
• Gene Symbols: CYP17A1
• Host Species: Goat
• Immunogen: A synthetic peptide corresponding to internal region of human CYP17A1.
• Purification Method: Antigen affinity purification
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 1586
• Target Species: Human
• Content And Storage: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid

For Research Use Only