DAP3, Goat, Polyclonal Antibody, Abnova™

Goat polyclonal antibody raised against synthetic peptide of DAP3.

Supplier:  Abnova Corporation PAB6163

Catalog No. 89-132-201

Description

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that also participates in apoptotic pathways which are initiated by tumor necrosis factor-alpha, Fas ligand, and gamma interferon. This protein potentially binds ATP/GTP and might be a functional partner of the mitoribosomal protein S27. Splice variants that differ in the 5' UTR have been found for this gene; both variants encode the same protein. Pseudogenes corresponding to this gene are found on chromosomes 1q and 2q. [provided by RefSeq]

Sequence: NPSLLERHCAYL

Specifications

• Antigen: DAP3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Dilution: ELISA (1:16000) Western blot (1-3 ug/mL) The optimal working dilution should be determined by the end user.
• Gene: DAP3
• Gene Alias: DAP-3/DKFZp686G12159/MGC126058/MGC126059/MRP-S29/MRPS29/bMRP-10
• Host Species: Goat
• Purification Method: Antigen affinity purification
• Regulatory Status: RUO
• Gene ID (Entrez): 7818
• Target Species: Human
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 0.5 mg/mL
• Description: Goat polyclonal antibody raised against synthetic peptide of DAP3.
• Formulation: In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
• Gene Accession No.: NP_387506.1;NP_004623.1
• Gene Symbols: DAP3
• Immunogen: A synthetic peptide corresponding to human DAP3.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Test Specificity: This antibody is expected to recognize both human isoforms of this protein.
• Content And Storage: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.

For Research Use Only