DMP1, Goat, Polyclonal Antibody, Abnova™

Catalog No.	Quantity
89-115-149	100 μg

Catalog No. 89-115-149 Supplier Abnova Corporation Supplier No. PAB11518

Description

Goat polyclonal antibody raised against synthetic peptide of DMP1.

Dentin matrix acidic phosphoprotein is an extracellular matrix protein and a member of the small integrin binding ligand N-linked glycoprotein family. This protein, which is critical for proper mineralization of bone and dentin, is present in diverse cells of bone and tooth tissues. The protein contains a large number of acidic domains, multiple phosphorylation sites, a functional arg-gly-asp cell attachment sequence, and a DNA binding domain. In undifferentiated osteoblasts it is primarily a nuclear protein that regulates the expression of osteoblast-specific genes. During osteoblast maturation the protein becomes phosphorylated and is exported to the extracellular matrix, where it orchestrates mineralized matrix formation. Mutations in the gene are known to cause autosomal recessive hypophosphatemia, a disease that manifests as rickets and osteomalacia. The gene structure is conserved in mammals. Two transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq

Sequence: C-ENSEQANTQDSG

Specifications

• Antigen: DMP1
• Applications: ELISA, Western Blot
• Classification: Polyclonal
• Concentration: 0.5 mg/mL
• Conjugate: Unconjugated
• Description: Goat polyclonal antibody raised against synthetic peptide of DMP1.
• Dilution: ELISA (1:4000) Western Blot (1-3 ug/mL) The optimal working dilution should be determined by the end user.
• Formulation: In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
• Gene: DMP1
• Gene Accession No.: NP_004398.1;NP_001073380.1
• Gene Alias: DMP-1
• Gene Symbols: DMP1
• Host Species: Goat
• Immunogen: A synthetic peptide corresponding to human DMP1.
• Purification Method: Antigen affinity purification
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 1758
• Target Species: Human
• Content And Storage: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid

For Research Use Only