DYRK1A, Goat, Polyclonal Antibody, Abnova™

Catalog No.	Quantity
89-129-032	100 μg

Catalog No. 89-129-032 Supplier Abnova Corporation Supplier No. PAB27523

Description

Goat polyclonal antibody raised against synthetic peptide of DYRK1A.

This gene encodes a member of the Dual-specificity tyrosine phosphorylation-regulated kinase (DYRK) family. This member contains a nuclear targeting signal sequence, a protein kinase domain, a leucine zipper motif, and a highly conservative 13-consecutive-histidine repeat. It catalyzes its autophosphorylation on serine/threonine and tyrosine residues. It may play a significant role in a signaling pathway regulating cell proliferation and may be involved in brain development. This gene is a homolog of Drosophila mnb (minibrain) gene and rat Dyrk gene. It is localized in the Down syndrome critical region of chromosome 21, and is considered to be a strong candidate gene for learning defects associated with Down syndrome. Alternative splicing of this gene generates several transcript variants differing from each other either in the 5' UTR or in the 3' coding region. These variants encode at least five different isoforms. [provided by RefSeq]

Sequence: PHSHQYSDRRQPN

Specifications

• Antigen: DYRK1A
• Applications: Western Blot
• Classification: Polyclonal
• Concentration: 0.5 mg/mL
• Conjugate: Unconjugated
• Description: Goat polyclonal antibody raised against synthetic peptide of DYRK1A.
• Dilution: ELISA (1:64000) Western Blot (0.5-2ug/ml) The optimal working dilution should be determined by the end user.
• Formulation: In Tris saline, pH 7.3 (0.02% sodium azide, 0.5% BSA)
• Gene: DYRK1A
• Gene Accession No.: NP_001387.2;NP_569120.1;NP_567824.1;NP_569122.1
• Gene Alias: DYRK/DYRK1/HP86/MNB/MNBH
• Gene Symbols: DYRK1A
• Host Species: Goat
• Immunogen: A synthetic peptide corresponding to N-terminus of human DYRK1A.
• Purification Method: Affinity Purified
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 1859
• Target Species: Canine, Chicken, Human, Mouse, Pig, Rat
• Content And Storage: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.

For Research Use Only