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Description
ETFA participates in catalyzing the initial step of the mitochondrial fatty acid beta-oxidation. It shuttles electrons between primary flavoprotein dehydrogenases and the membrane-bound electron transfer flavoprotein ubiquinone oxidoreductase. Defects in electron-transfer-flavoprotein have been implicated in type II glutaricaciduria in which multiple acyl-CoA dehydrogenase deficiencies result in large excretion of glutaric, lactic, ethylmalonic, butyric, isobutyric, 2-methyl-butyric, and isovaleric acids. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Specifications
Specifications
| Antigen | ETFA |
| Applications | ELISA, Western Blot |
| Classification | Polyclonal |
| Concentration | 0.5 mg/mL |
| Conjugate | Unconjugated |
| Description | Goat polyclonal antibody raised against synthetic peptide of ETFA. |
| Dilution | ELISA (1:16000) Western Blot (0.1-0.3 ug/mL) The optimal working dilution should be determined by the end user. |
| Formulation | In 0.5mg/mL in Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide) |
| Gene | ETFA |
| Gene Accession No. | NP_000117.1;NP_001121188.1 |
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