EWSR1, Goat, Polyclonal Antibody, Abnova™

Catalog No.	Quantity
89-115-218	100 μg

Catalog No. 89-115-218 Supplier Abnova Corporation Supplier No. PAB11611

Description

Goat polyclonal antibody raised against synthetic peptide of EWSR1.

This gene encodes a multifunctional protein that is involved in various cellular processes, including gene expression, cell signaling, and RNA processing and transport. The protein includes an N-terminal transcriptional activation domain and a C-terminal RNA-binding domain. Chromosomal translocations between this gene and various genes encoding transcription factors result in the production of chimeric proteins that are involved in tumorigenesis. These chimeric proteins usually consist of the N-terminal transcriptional activation domain of this protein fused to the C-terminal DNA-binding domain of the transcription factor protein. Mutations in this gene, specifically a t(11;22)(q24;q12) translocation, are known to cause Ewing sarcoma as well as neuroectodermal and various other tumors. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 1 and 14. [provided by RefSeq

Sequence: C-TSYDQSSYSQQNTYG

Specifications

• Antigen: EWSR1
• Applications: ELISA, Western Blot
• Classification: Polyclonal
• Concentration: 0.5 mg/mL
• Conjugate: Unconjugated
• Description: Goat polyclonal antibody raised against synthetic peptide of EWSR1.
• Dilution: ELISA (1:16000) Western Blot (1-3 ug/mL) The optimal working dilution should be determined by the end user.
• Formulation: In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
• Gene: EWSR1
• Gene Accession No.: NP_053733.1;NP_005234.1
• Gene Alias: EWS
• Gene Symbols: EWSR1
• Host Species: Goat
• Immunogen: A synthetic peptide corresponding to human EWSR1.
• Purification Method: Antigen affinity purification
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 2130
• Target Species: Human
• Content And Storage: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid

For Research Use Only