FOXP2 Goat anti-Human, Rat, Polyclonal Antibody, Abnova™

Catalog No.	Quantity
89-133-001	100 μg

Catalog No. 89-133-001 Supplier Abnova Corporation Supplier No. PAB7158

Description

Goat polyclonal antibody raised against synthetic peptide of FOXP2.

This gene encodes an evolutionarily conserved transcription factor expressed in fetal and adult brain. This transcription factor is a member of the forkhead/winged-helix (FOX) family of transcription factors, and contains a FOX DNA-binding domain and a large polyglutamine tract. Members of the FOX family of transcription factors are regulators of embryogenesis. The product of this gene is thought to be required for proper development of speech and language regions of the brain during embryogenesis. Although a point mutation in this gene has been associated with the KE pedigree segregating developmental verbal dyspraxia, no association between mutations in this gene and another speech disorder, autism, has been found. Multiple alternative transcripts encoding different isoforms have been identified. [provided by RefSeq

Sequence: C-DEVEYQKRRSQKIT

Specifications

• Antigen: FOXP2
• Applications: ELISA, Immunohistochemistry (PFA fixed), Western Blot
• Classification: Polyclonal
• Concentration: 0.5 mg/mL
• Conjugate: Unconjugated
• Description: Goat polyclonal antibody raised against synthetic peptide of FOXP2.
• Dilution: ELISA (1:64000) Western Blot (0.3-1 ug/mL) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (2-4 ug/mL) The optimal working dilution should be determined by the end user.
• Formulation: In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
• Gene: FOXP2
• Gene Accession No.: NP_055306.1;NP_683696.2;NP_683697.2;NP_683698.2;NP_001166237.1
• Gene Alias: CAGH44/DKFZp686H1726/SPCH1/TNRC10
• Gene Symbols: FOXP2
• Host Species: Goat
• Immunogen: A synthetic peptide corresponding to internal region of human FOXP2.
• Purification Method: Antigen affinity purification
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 93986
• Test Specificity: This antibody is expected to recognize isoform I (NP_055306.1), isoform II (NP_683696.1) and isoform III (NP_683697.1 and NP_683698.1).
• Target Species: Human, Rat
• Content And Storage: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid

For Research Use Only