GAD1 Goat anti-Chicken, Dog, Human, Mouse, Pig, Rat, Polyclonal Antibody, Abnova™

Catalog No.	Quantity
89-129-085	100 μg

Catalog No. 89-129-085 Supplier Abnova Corporation Supplier No. PAB27574

Description

Goat polyclonal antibody raised against synthetic peptide of GAD1.

This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantigen and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Deficiency in this enzyme has been shown to lead to pyridoxine dependency with seizures. Alternative splicing of this gene results in two products, the predominant 67kDa form and a less-frequent 25kDa form. [provided by RefSeq

Sequence: QRTNSLEEKSR

Specifications

• Antigen: GAD1
• Applications: Western Blot
• Classification: Polyclonal
• Concentration: 0.5 mg/mL
• Conjugate: Unconjugated
• Description: Goat polyclonal antibody raised against synthetic peptide of GAD1.
• Dilution: ELISA (1:8000) Western Blot (1-3ug/ml) The optimal working dilution should be determined by the end user.
• Formulation: In Tris saline, pH 7.3 (0.02% sodium azide, 0.5% BSA)
• Gene: GAD1
• Gene Accession No.: NP_038473.2;NP_000808.2
• Gene Alias: FLJ45882/GAD/SCP
• Gene Symbols: GAD1
• Host Species: Goat
• Immunogen: A synthetic peptide corresponding to internal region of human GAD1.
• Purification Method: Affinity Purified
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 2571
• Target Species: Canine, Chicken, Human, Mouse, Pig, Rat
• Content And Storage: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.

For Research Use Only