GJB6, Goat, Polyclonal Antibody, Abnova™

Catalog No.	Quantity
89-118-934	100 μg

Catalog No. 89-118-934 Supplier Abnova Corporation Supplier No. PAB17269

Description

Goat polyclonal antibody raised against synthetic peptide of GJB6.

Gap junctions allow the transport of ions and metabolites between the cytoplasm of adjacent cells. They are formed by two hemichannels, made up of six connexin proteins assembled in groups. Each connexin protein has four transmembrane segments, two extracellular loops, a cytoplasmic loop formed between the two inner transmembrane segments, and the N- and C-terminus both being in the cytoplasm. The specificity of the gap junction is determined by which connexin proteins comprise the hemichannel. In the past, connexin protein names were based on their molecular weight, however the new nomenclature uses sequential numbers based on which form (alpha or beta) of the gap junction is present. This gene encodes one of the connexin proteins. Mutations in this gene have been found in some forms of deafness and in some families with hidrotic ectodermal dysplasia. [provided by RefSeq

Sequence: C-RSKRAQTQKNHPNH

Specifications

• Antigen: GJB6
• Applications: ELISA
• Classification: Polyclonal
• Concentration: 0.5 mg/mL
• Conjugate: Unconjugated
• Description: Goat polyclonal antibody raised against synthetic peptide of GJB6.
• Dilution: ELISA (1:16000) The optimal working dilution should be determined by the end user.
• Formulation: In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
• Gene: GJB6
• Gene Accession No.: NP_006774.2
• Gene Alias: CX30/DFNA3/ED2/EDH/HED
• Gene Symbols: GJB6
• Host Species: Goat
• Immunogen: A synthetic peptide corresponding to amino acids at internal region of human GJB6.
• Purification Method: Antigen affinity purification
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 10804
• Test Specificity: Reported variants represent identical protein: NP_006774.2, NP_001103691.1, NP_001103689.1, NP_001103690.1
• Target Species: Human
• Content And Storage: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid

For Research Use Only