GPX4, Goat, Polyclonal Antibody, Abnova™

Goat polyclonal antibody raised against synthetic peptide of GPX4.

Supplier:  Abnova Corporation PAB7065

Catalog No. 89-132-921

Description

Glutathione peroxidase catalyzes the reduction of hydrogen peroxide, organic hydroperoxide, and lipid peroxides by reduced glutathione and functions in the protection of cells against oxidative damage. Human plasma glutathione peroxidase has been shown to be a selenium-containing enzyme and the UGA codon is translated into a selenocysteine. Through alternative splicing and transcription initiation, rat produces proteins that localize to the nucleus, mitochondrion, and cytoplasm. In humans, experimental evidence for alternative splicing exists; alternative transcription initiation and the cleavage sites of the mitochondrial and nuclear transit peptides need to be experimentally verified. [provided by RefSeq

Sequence: C-EEPLVIEKDLPHY

Specifications

• Antigen: GPX4
• Classification: Polyclonal
• Conjugate: Unconjugated
• Dilution: ELISA (1:16000) Western blot (0.1-0.3 ug/mL) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (0.3 ug/mL) The optimal working dilution should be determined by the end user.
• Gene: GPX4
• Gene Alias: MCSP/PHGPx/snGPx/snPHGPx
• Host Species: Goat
• Purification Method: Antigen affinity purification
• Regulatory Status: RUO
• Gene ID (Entrez): 2879
• Target Species: Human
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (PFA fixed), Western Blot
• Concentration: 0.5 mg/mL
• Description: Goat polyclonal antibody raised against synthetic peptide of GPX4.
• Formulation: In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
• Gene Accession No.: NP_002076.2;NP_0010.34937.1
• Gene Symbols: GPX4
• Immunogen: A synthetic peptide corresponding to C-terminus of human GPX4.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Test Specificity: This antibody is expected to recognize isoform A (NP_002076.2) and isoform C (NP_0010.34937.1).
• Content And Storage: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.

For Research Use Only