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GRB2, Goat, Polyclonal Antibody, Abnova™

Catalog No. 89132138 Shop All Abnova Corporation Products
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89-132-138 100 μg
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Catalog No. 89-132-138 Supplier Abnova Corporation Supplier No. PAB6094
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Goat polyclonal antibody raised against synthetic peptide of GRB2.

The protein encoded by this gene binds the epidermal growth factor receptor and contains one SH2 domain and two SH3 domains. Its two SH3 domains direct complex formation with proline-rich regions of other proteins, and its SH2 domain binds tyrosine phosphorylated sequences. This gene is similar to the Sem5 gene of C. elegans, which is involved in the signal transduction pathway. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq

Sequence: C-PRNYVTPVNRNV

Specifications

Antigen GRB2
Applications ELISA, Immunohistochemistry (PFA fixed), Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Description Goat polyclonal antibody raised against synthetic peptide of GRB2.
Dilution ELISA (1:32000) Western Blot (1-3 ug/mL) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (0.1-0.3 ug/mL) The optimal working dilution should be determined by the end user.
Formulation In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Gene GRB2
Gene Accession No. NP_002077.1;NP_987102.1
Gene Alias ASH/EGFRBP-GRB2/Grb3-3/MST084/MSTP084
Gene Symbols GRB2
Host Species Goat
Immunogen A synthetic peptide corresponding to C-terminus of human GRB2.
Purification Method Antigen affinity purification
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2885
Test Specificity This antibody is expected to recognize both reported isoforms (NP_002077.1and NP_987102.1).
Target Species Human, Mouse
Content And Storage Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
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For Research Use Only

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