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GRM7, Goat, Polyclonal Antibody, Abnova™

Catalog No. 89116106 Shop All Abnova Corporation Products
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100 μg
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89-116-106 100 μg
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Catalog No. 89-116-106 Supplier Abnova Corporation Supplier No. PAB12813
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Description

Goat polyclonal antibody raised against synthetic peptide of GRM7.

L-glutamate is the major excitatory neurotransmitter in the central nervous system, and it activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors that have been divided into three groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5, and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3, while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq

Sequence: NCKLTISGSKKEDT

Specifications

Antigen GRM7
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Description Goat polyclonal antibody raised against synthetic peptide of GRM7.
Dilution ELISA (1:32000) Western blot (0.5-2 ug/mL) The optimal working dilution should be determined by the end user.
Formulation In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Gene GRM7
Gene Accession No. NP_000835.1;NP_870989.1
Gene Alias FLJ40498/GLUR7/GPRC1G/MGLUR7/mGlu7
Gene Symbols GRM7
Host Species Goat
Immunogen A synthetic peptide corresponding to amino acids at internal region of human GRM7.
Purification Method Antigen affinity purification
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2917
Test Specificity This antibody is expected to recognize both reported isoforms (NP_000835.1; NP_870989.1). 100 KDa band observed in human Brain (Cerebellum) and in Mouse and Rat Brain lysates (calculated MW of 102 KDa according to NP_000835.1).
Target Species Human
Content And Storage Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
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For Research Use Only

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