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Description
This gene is a member of the Abd-B homeobox family and encodes a protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox D genes located on chromosome 2. The encoded nuclear protein functions as a sequence-specific transcription factor that is expressed in the developing limb buds and is involved in differentiation and limb development. Mutations in this gene have been associated with Wilm's tumor and congenital vertical talus (also known as rocker-bottom foot deformity or congenital convex pes valgus) and/or a foot deformity resembling that seen in Charcot-Marie-Tooth disease. [provided by RefSeq]
Specifications
Specifications
| Antigen | HOXD10 |
| Applications | ELISA, Immunohistochemistry (PFA fixed), Western Blot |
| Classification | Polyclonal |
| Conjugate | Unconjugated |
| Description | Goat polyclonal antibody raised against synthetic peptide of HOXD10. |
| Dilution | Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)(3-5 ug/mL) ELISA (1:32000) Western Blot (0.2-0.6 ug/mL) The optimal working dilution should be determined by the end user. |
| Formulation | In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide) |
| Gene | HOXD10 |
| Gene Alias | HOX4/HOX4D/HOX4E/Hox-4.4 |
| Gene Symbols | HOXD10 |
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