HP Goat anti-Human, Polyclonal Antibody, Abnova™

Catalog No.	Quantity
89-126-308	100 μg

Catalog No. 89-126-308 Supplier Abnova Corporation Supplier No. PAB24591

Description

Goat polyclonal antibody raised against synthetic peptide of HP.

This gene encodes a preproprotein, which is processed to yield both alpha and beta chains, which subsequently combine as a tetramer to produce haptoglobin. Haptoglobin functions to bind free plasma hemoglobin, which allows degradative enzymes to gain access to the hemoglobin, while at the same time preventing loss of iron through the kidneys and protecting the kidneys from damage by hemoglobin. Mutations in this gene and/or its regulatory regions cause ahaptoglobinemia or hypohaptoglobinemia. This gene has also been linked to diabetic nephropathy, the incidence of coronary artery disease in type 1 diabetes, Crohn's disease, inflammatory disease behavior, primary sclerosing cholangitis, susceptibility to idiopathic Parkinson's disease, and a reduced incidence of Plasmodium falciparum malaria. A similar duplicated gene is located next to this gene on chromosome 16. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Sequence: C-STVPEKKTPKSP

Specifications

• Antigen: HP
• Applications: ELISA, Western Blot
• Classification: Polyclonal
• Conjugate: Unconjugated
• Description: Goat polyclonal antibody raised against synthetic peptide of HP.
• Dilution: ELISA (1:8000) Western Blot (0.1-0.3 ug/mL) The optimal working dilution should be determined by the end user.
• Formulation: In 0.5mg/mL Tris saline, pH 7.3 (0.02% sodium azide, 0.5% BSA)
• Gene: HP
• Gene Alias: BP/HP2-ALPHA-2/HPA1S/MGC111141
• Gene Symbols: HP
• Host Species: Goat
• Immunogen: A synthetic peptide corresponding to internal region of human HP.
• Purification Method: Antigen affinity purification
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 3240
• Test Specificity: This antibody is expected to recognize both reported isoforms (NP_005134.1; NP_001119574.1).
• Target Species: Human
• Content And Storage: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid

For Research Use Only