IDH1 Goat anti-Human, Polyclonal Antibody, Abnova™

Catalog No.	Quantity
89-120-521	100 μg

Catalog No. 89-120-521 Supplier Abnova Corporation Supplier No. PAB18969

Description

Goat polyclonal antibody raised against synthetic peptide of IDH1.

Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. Each NADP(+)-dependent isozyme is a homodimer. The protein encoded by this gene is the NADP(+)-dependent isocitrate dehydrogenase found in the cytoplasm and peroxisomes. It contains the PTS-1 peroxisomal targeting signal sequence. The presence of this enzyme in peroxisomes suggests roles in the regeneration of NADPH for intraperoxisomal reductions, such as the conversion of 2, 4-dienoyl-CoAs to 3-enoyl-CoAs, as well as in peroxisomal reactions that consume 2-oxoglutarate, namely the alpha-hydroxylation of phytanic acid. The cytoplasmic enzyme serves a significant role in cytoplasmic NADPH production. [provided by RefSeq]

Sequence: C-EITYTPSDGTQK

Specifications

• Antigen: IDH1
• Applications: ELISA, Western Blot
• Classification: Polyclonal
• Concentration: 0.5 mg/mL
• Conjugate: Unconjugated
• Description: Goat polyclonal antibody raised against synthetic peptide of IDH1.
• Dilution: ELISA (1:1000) Western Blot (0.3-1 ug/mL) The optimal working dilution should be determined by the end user.
• Formulation: In 0.5mg/mL in Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
• Gene: IDH1
• Gene Alias: IDCD/IDH/IDP/IDPC/PICD
• Gene Symbols: IDH1
• Host Species: Goat
• Immunogen: A synthetic peptide corresponding to amino acids at internal region of human IDH1.
• Purification Method: Antigen affinity purification
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 3417
• Target Species: Human
• Content And Storage: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid

For Research Use Only