IDH3B Goat anti-Mouse, Polyclonal Antibody, Abnova™

Catalog No.	Quantity
89-121-282	100 μg

Catalog No. 89-121-282 Supplier Abnova Corporation Supplier No. PAB19754

Description

Goat polyclonal antibody raised against synthetic peptide of IDH3B.

Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. NAD(+)-dependent isocitrate dehydrogenases catalyze the allosterically regulated rate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer that is composed of two alpha subunits, one beta subunit, and one gamma subunit. The protein encoded by this gene is the beta subunit of one isozyme of NAD(+)-dependent isocitrate dehydrogenase. Three alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq]

Sequence: CTTDFIKSVIGHLQTK

Specifications

• Antigen: IDH3B
• Applications: ELISA, Western Blot
• Classification: Polyclonal
• Concentration: 0.5 mg/mL
• Conjugate: Unconjugated
• Description: Goat polyclonal antibody raised against synthetic peptide of IDH3B.
• Dilution: ELISA (1:16000) Western Blot (0.03-0.1 ug/mL) The optimal working dilution should be determined by the end user.
• Formulation: In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
• Gene: IDH3B
• Gene Alias: FLJ11043/H-IDHB/MGC903
• Gene Symbols: IDH3B
• Host Species: Goat
• Immunogen: A synthetic peptide correspoding to amino acids 369-383 at C-terminus of human IDH3B.
• Purification Method: Antigen affinity purification
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 3420
• Test Specificity: This antibody is expected to recognize isoform a (NP_008830.2) and isoform c (NP_777281.1).
• Target Species: Human
• Content And Storage: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid

For Research Use Only