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IL15, Goat, Polyclonal Antibody, Abnova™

Catalog No. 89129149 Shop All Abnova Corporation Products
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89-129-149 100 μg
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Catalog No. 89-129-149 Supplier Abnova Corporation Supplier No. PAB27637
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Goat polyclonal antibody raised against synthetic peptide of IL15.

The protein encoded by this gene is a cytokine that regulates T and natural killer cell activation and proliferation. This cytokine and interleukine 2 share many biological activities. They are found to bind common hematopoietin receptor subunits, and may compete for the same receptor, and thus negatively regulate each other's activity. The number of CD8+ memory cells is shown to be controlled by a balance between this cytokine and IL2. This cytokine induces the activation of JAK kinases, as well as the phosphorylation and activation of transcription activators STAT3, STAT5, and STAT6. Studies of the mouse counterpart suggested that this cytokine may increase the expression of apoptosis inhibitor BCL2L1/BCL-x(L), possibly through the transcription activation activity of STAT6, and thus prevent apoptosis. Two alternatively spliced transcript variants of this gene encoding the same protein have been reported. [provided by RefSeq]

Sequence: DATLYTESDVHPS

Specifications

Antigen IL15
Applications Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Description Goat polyclonal antibody raised against synthetic peptide of IL15.
Dilution ELISA (1:128000) Western Blot (1-3ug/ml) The optimal working dilution should be determined by the end user.
Formulation In Tris saline, pH 7.3 (0.02% sodium azide, 0.5% BSA)
Gene IL15
Gene Alias IL-15/MGC9721
Gene Symbols IL15
Host Species Goat
Immunogen A synthetic peptide corresponding to amino acids 70-82 at internal region of human IL15.
Purification Method Affinity Purified
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3600
Target Species Human
Content And Storage Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
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