IL6R, Goat, Polyclonal Antibody, Abnova™

Catalog No.	Quantity
89-132-830	100 μg

Catalog No. 89-132-830 Supplier Abnova Corporation Supplier No. PAB6961

Description

Goat polyclonal antibody raised against synthetic peptide of IL6R.

Interleukin 6 (IL6) is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in immune response. The protein encoded by this gene is a subunit of the receptor complex for IL6. The IL6 receptor is a protein complex consisting of this protein and interleukin 6 signal transducer (IL6ST/GP130/IL6-beta), a receptor subunit also shared by many other cytokines. Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq

Sequence: C-DNTSSHNRPDARD

Specifications

• Antigen: IL6R
• Applications: ELISA
• Classification: Polyclonal
• Concentration: 0.5 mg/mL
• Conjugate: Unconjugated
• Description: Goat polyclonal antibody raised against synthetic peptide of IL6R.
• Dilution: ELISA (1:8000) The optimal working dilution should be determined by the end user.
• Formulation: In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
• Gene: IL6R
• Gene Alias: CD126/IL-6R-1/IL-6R-alpha/IL6RA/MGC104991
• Gene Symbols: IL6R
• Host Species: Goat
• Immunogen: A synthetic peptide corresponding to human IL6R.
• Purification Method: Antigen affinity purification
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 3570
• Test Specificity: This antibody is expected to recognize isoform 1 only (NP_000556.1).
• Target Species: Human
• Content And Storage: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid

For Research Use Only