ITCH, Goat, Polyclonal Antibody, Abnova™

Catalog No.	Quantity
89-133-052	100 μg

Catalog No. 89-133-052 Supplier Abnova Corporation Supplier No. PAB7215

Description

Goat polyclonal antibody raised against synthetic peptide of ITCH.

Atrophin-1 contains a polyglutamine repeat, expansion of which is responsible for dentatorubral and pallidoluysian atrophy. The protein encoded by this gene interacts with atrophin-1. This encoded protein is a closely related member of the NEDD4-like protein family. This family of proteins are E3 ubiquitin-ligase molecules and regulate key trafficking decisions, including targeting of proteins to proteosomes or lysosomes. This encoded protein contains four tandem WW domains and a HECT (homologous to the E6-associated protein carboxyl terminus) domain. It can act as a transcriptional corepressor of p45/NFE2 and may participate in the regulation of immune responses by modifying Notch-mediated signaling. It is highly similar to the mouse Itch protein, which has been implicated in the regulation and differentiation of erythroid and lymphoid cells. [provided by RefSeq

Sequence: C-EIKSHDLKPNGGN

Specifications

• Antigen: ITCH
• Applications: ELISA, Western Blot
• Classification: Polyclonal
• Concentration: 0.5 mg/mL
• Conjugate: Unconjugated
• Description: Goat polyclonal antibody raised against synthetic peptide of ITCH.
• Dilution: ELISA (1:32000) Western Blot (0.03-0.1 ug/mL) The optimal working dilution should be determined by the end user.
• Formulation: In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
• Gene: ITCH
• Gene Alias: AIF4/AIP4/NAPP1/dJ468O1.1
• Gene Symbols: ITCH
• Host Species: Goat
• Immunogen: A synthetic peptide corresponding to human ITCH.
• Purification Method: Antigen affinity purification
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 83737
• Target Species: Human
• Content And Storage: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid

For Research Use Only