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KCNJ11, Goat, Polyclonal Antibody, Abnova™

Catalog No. 89133375 Shop All Abnova Corporation Products
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100 μg
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89-133-375 100 μg
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Catalog No. 89-133-375 Supplier Abnova Corporation Supplier No. PAB7570
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Description

Goat polyclonal antibody raised against synthetic peptide of KCNJ11.

Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, is controlled by G-proteins and is found associated with the sulfonylurea receptor SUR. Mutations in this gene are a cause of familial persistent hyperinsulinemic hypoglycemia of infancy (PHHI), an autosomal recessive disorder characterized by unregulated insulin secretion. Defects in this gene may also contribute to autosomal dominant noninsulin-dependent diabetes mellitus type II (NIDDM), transient neonatal diabetes mellitus type 3 (TNDM3), and permanent neonatal diabetes mellitus (PNDM). [provided by RefSeq

Sequence: C-AEDPAKPRYRARQ

Specifications

Antigen KCNJ11
Applications ELISA, Immunohistochemistry (PFA fixed), Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Description Goat polyclonal antibody raised against synthetic peptide of KCNJ11.
Dilution ELISA (1:32000) Western blot (0.1-0.3 ug/mL) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (3-5 ug/mL) The optimal working dilution should be determined by the end user.
Formulation In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Gene KCNJ11
Gene Alias BIR/HHF2/IKATP/KIR6.2/MGC133230/PHHI/TNDM3
Gene Symbols KCNJ11
Host Species Goat
Immunogen A synthetic peptide corresponding to human KCNJ11.
Purification Method Antigen affinity purification
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3767
Target Species Human
Content And Storage Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
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For Research Use Only

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