KCNQ4, Goat, Polyclonal Antibody, Abnova™

Goat polyclonal antibody raised against synthetic peptide of KCNQ4.

Supplier:  Abnova Corporation PAB11544

Catalog No. 89-115-168

Description

The protein encoded by this gene forms a potassium channel that is thought to play a critical role in the regulation of neuronal excitability, particularly in sensory cells of the cochlea. The current generated by this channel is inhibited by M1 muscarinic acetylcholine receptors and activated by retigabine, a novel anti-convulsant drug. The encoded protein can form a homomultimeric potassium channel or possibly a heteromultimeric channel in association with the protein encoded by the KCNQ3 gene. Defects in this gene are a cause of nonsyndromic sensorineural deafness type 2 (DFNA2), an autosomal dominant form of progressive hearing loss. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq

Sequence: C-DKGPSDAEVVDE

Specifications

• Antigen: KCNQ4
• Classification: Polyclonal
• Conjugate: Unconjugated
• Dilution: ELISA (1:4000) Western Blot (1-3 ug/mL) The optimal working dilution should be determined by the end user.
• Gene: KCNQ4
• Gene Symbols: KCNQ4
• Immunogen: A synthetic peptide corresponding to human KCNQ4.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 0.5 mg/mL
• Description: Goat polyclonal antibody raised against synthetic peptide of KCNQ4.
• Formulation: In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
• Gene Alias: DFNA2/KV7.4
• Host Species: Goat
• Purification Method: Antigen affinity purification
• Regulatory Status: RUO
• Gene ID (Entrez): 9132
• Content And Storage: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.

For Research Use Only