KCNQ4, Goat, Polyclonal Antibody, Abnova™

Catalog No.	Quantity
89-115-168	100 μg

Catalog No. 89-115-168 Supplier Abnova Corporation Supplier No. PAB11544

Description

Goat polyclonal antibody raised against synthetic peptide of KCNQ4.

The protein encoded by this gene forms a potassium channel that is thought to play a critical role in the regulation of neuronal excitability, particularly in sensory cells of the cochlea. The current generated by this channel is inhibited by M1 muscarinic acetylcholine receptors and activated by retigabine, a novel anti-convulsant drug. The encoded protein can form a homomultimeric potassium channel or possibly a heteromultimeric channel in association with the protein encoded by the KCNQ3 gene. Defects in this gene are a cause of nonsyndromic sensorineural deafness type 2 (DFNA2), an autosomal dominant form of progressive hearing loss. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq

Sequence: C-DKGPSDAEVVDE

Specifications

• Antigen: KCNQ4
• Applications: ELISA, Western Blot
• Classification: Polyclonal
• Concentration: 0.5 mg/mL
• Conjugate: Unconjugated
• Description: Goat polyclonal antibody raised against synthetic peptide of KCNQ4.
• Dilution: ELISA (1:4000) Western Blot (1-3 ug/mL) The optimal working dilution should be determined by the end user.
• Formulation: In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
• Gene: KCNQ4
• Gene Alias: DFNA2/KV7.4
• Gene Symbols: KCNQ4
• Host Species: Goat
• Immunogen: A synthetic peptide corresponding to human KCNQ4.
• Purification Method: Antigen affinity purification
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 9132
• Target Species: Human
• Content And Storage: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid

For Research Use Only