LARGE Goat, Polyclonal Antibody, Abnova™

Goat polyclonal antibody raised against synthetic peptide of LARGE.

Manufacturer:  Abnova Corporation PAB18596

Catalog No. 89-120-154

Description

This gene, which is one of the largest in the human genome, encodes a member of the N-acetylglucosaminyltransferase gene family. It encodes a glycosyltransferase which participates in glycosylation of alpha-dystroglycan, and may carry out the synthesis of glycoprotein and glycosphingolipid sugar chains. It may also be involved in the addition of a repeated disaccharide unit. Mutations in this gene cause MDC1D, a novel form of congenital muscular dystrophy with severe mental retardation and abnormal glycosylation of alpha-dystroglycan. Alternative splicing of this gene results in two transcript variants that encode the same protein. [provided by RefSeq

Sequence: RYTASSQRERESLE-C

Specifications

• Antigen: LARGE
• Classification: Polyclonal
• Conjugate: Unconjugated
• Dilution: ELISA (1:32000) The optimal working dilution should be determined by the end user.
• Gene: LARGE
• Gene Symbols: LARGE
• Immunogen: A synthetic peptide corresponding to amino acids at N-terminus of human LARGE.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Test Specificity: Reported variants represent identical protein: NP_004728.1, NP_598397.1.
• Content And Storage: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.

• Applications: ELISA
• Concentration: 0.5 mg/mL
• Description: Goat polyclonal antibody raised against synthetic peptide of LARGE.
• Formulation: In 0.5mg/mL Tris saline, pH 7.3 (0.02% sodium azide, 0.5% BSA)
• Gene Alias: KIAA0609/MDC1D
• Host Species: Goat
• Purification Method: Antigen affinity purification
• Regulatory Status: RUO
• Gene ID (Entrez): 9215
• Target Species: Human
• Form: Liquid

For Research Use Only