LARGE Goat, Polyclonal Antibody, Abnova™
Goat polyclonal antibody raised against synthetic peptide of LARGE.
Manufacturer: Abnova Corporation PAB18596
This gene, which is one of the largest in the human genome, encodes a member of the N-acetylglucosaminyltransferase gene family. It encodes a glycosyltransferase which participates in glycosylation of alpha-dystroglycan, and may carry out the synthesis of glycoprotein and glycosphingolipid sugar chains. It may also be involved in the addition of a repeated disaccharide unit. Mutations in this gene cause MDC1D, a novel form of congenital muscular dystrophy with severe mental retardation and abnormal glycosylation of alpha-dystroglycan. Alternative splicing of this gene results in two transcript variants that encode the same protein. [provided by RefSeqSequence: RYTASSQRERESLE-C
|ELISA (1:32000) The optimal working dilution should be determined by the end user.|
|A synthetic peptide corresponding to amino acids at N-terminus of human LARGE.|
|Reported variants represent identical protein: NP_004728.1, NP_598397.1.|
|Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
|Goat polyclonal antibody raised against synthetic peptide of LARGE.|
|In 0.5mg/mL Tris saline, pH 7.3 (0.02% sodium azide, 0.5% BSA)|
|Antigen affinity purification|
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