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MAP3K7IP3 Goat, Polyclonal Antibody, Abnova™

Catalog No. 89133193 Shop All Abnova Corporation Products
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89-133-193 100 μg
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Catalog No. 89-133-193 Supplier Abnova Corporation Supplier No. PAB7373
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Goat polyclonal antibody raised against synthetic peptide of MAP3K7IP3.

The product of this gene functions in the NF-kappaB signal transduction pathway. The encoded protein, and the similar and functionally redundant protein MAP3K7IP2/TAB2, forms a ternary complex with the protein kinase MAP3K7/TAK1 and either TRAF2 or TRAF6 in response to stimulation with the pro-inflammatory cytokines TNF or IL-1. Subsequent MAP3K7/TAK1 kinase activity triggers a signaling cascade leading to activation of the NF-kappaB transcription factor. The human genome contains a related pseudogene. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq

Sequence: C-NYQPSQYSPKQQ

Specifications

Antigen MAP3K7IP3
Applications ELISA
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Description Goat polyclonal antibody raised against synthetic peptide of MAP3K7IP3.
Dilution ELISA (1:8000) The optimal working dilution should be determined by the end user.
Formulation In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Gene MAP3K7IP3
Gene Alias MGC45404/NAP1/TAB3
Gene Symbols MAP3K7IP3
Host Species Goat
Immunogen A synthetic peptide corresponding to amino acids 274-285 of human MAP3K7IP3.
Purification Method Antigen affinity purification
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 257397
Target Species Human
Content And Storage Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
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For Research Use Only

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