MYLK, Goat, Polyclonal Antibody, Abnova™

Catalog No.	Quantity
89-126-312	100 μg

Catalog No. 89-126-312 Supplier Abnova Corporation Supplier No. PAB24595

Description

Goat polyclonal antibody raised against synthetic peptide of MYLK.

This gene, a muscle member of the immunoglobulin gene superfamily, encodes myosin light chain kinase which is a calcium/calmodulin dependent enzyme. This kinase phosphorylates myosin regulatory light chains to facilitate myosin interaction with actin filaments to produce contractile activity. This gene encodes both smooth muscle and nonmuscle isoforms. In addition, using a separate promoter in an intron in the 3' region, it encodes telokin, a small protein identical in sequence to the C-terminus of myosin light chain kinase, that is independently expressed in smooth muscle and functions to stabilize unphosphorylated myosin filaments. A pseudogene is located on the p arm of chromosome 3. Four transcript variants that produce four isoforms of the calcium/calmodulin dependent enzyme have been identified as well as two transcripts that produce two isoforms of telokin. Additional variants have been identified but lack full length transcripts. [provided by RefSeq]

Sequence: C-KDTKNMEAKKLSKD

Specifications

• Antigen: MYLK
• Applications: ELISA, Western Blot
• Classification: Polyclonal
• Conjugate: Unconjugated
• Description: Goat polyclonal antibody raised against synthetic peptide of MYLK.
• Dilution: ELISA (1:8000) Western Blot (0.01-0.03 ug/mL) The optimal working dilution should be determined by the end user.
• Formulation: In 0.5mg/mL Tris saline, pH 7.3 (0.02% sodium azide, 0.5% BSA)
• Gene: MYLK
• Gene Alias: DKFZp686I10125/FLJ12216/KRP/MLCK/MLCK1/MLCK108/MLCK210/MSTP083/MYLK1/smMLCK
• Gene Symbols: MYLK
• Host Species: Goat
• Immunogen: A synthetic peptide corresponding to internal region of human MYLK.
• Purification Method: Antigen affinity purification
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 4638
• Test Specificity: This antibody is expected to recognize all reported isoforms (NP_444253.3; NP_444254.3 ; NP_444255.3 and NP_444256.3).
• Target Species: Human
• Content And Storage: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid

For Research Use Only