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Description
NEIL1 belongs to a class of DNA glycosylases homologous to the bacterial Fpg/Nei family. These glycosylases initiate the first step in base excision repair by cleaving bases damaged by reactive oxygen species and introducing a DNA strand break via the associated lyase reaction (Bandaru et al., 2002 [PubMed 12509226]).[supplied by OMIM
Specifications
Specifications
| Antigen | NEIL1 |
| Applications | ELISA, Immunohistochemistry (PFA fixed) |
| Classification | Polyclonal |
| Concentration | 0.5 mg/mL |
| Conjugate | Unconjugated |
| Description | Goat polyclonal antibody raised against synthetic peptide of NEIL1. |
| Dilution | ELISA (1:16000) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (5-10 ug/mL) The optimal working dilution should be determined by the end user. |
| Formulation | In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide) |
| Gene | NEIL1 |
| Gene Alias | FLJ22402/FPG1/NEI1/hFPG1 |
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