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NFASC, Goat, Polyclonal Antibody, Abnova™

Catalog No. 89121209 Shop All Abnova Corporation Products
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89-121-209 100 μg
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Catalog No. 89-121-209 Supplier Abnova Corporation Supplier No. PAB19682
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Goat polyclonal antibody raised against synthetic peptide of NFASC.

This gene encodes an L1 family immunoglobulin cell adhesion molecule with multiple IGcam and fibronectin domains. The protein functions in neurite outgrowth, neurite fasciculation, and organization of the axon initial segment (AIS) and nodes of Ranvier on axons during early development. Both the AIS and nodes of Ranvier contain high densities of voltage-gated Na+ (Nav) channels which are clustered by interactions with cytoskeletal and scaffolding proteins including this protein, gliomedin, ankyrin 3 (ankyrin-G), and betaIV spectrin. This protein links the AIS extracellular matrix to the intracellular cytoskeleton. This gene undergoes extensive alternative splicing, and the full-length nature of some variants has not been determined

Sequence: C-NFSPNQTKFTVQRT

Specifications

Antigen NFASC
Applications ELISA, Western Blot
Classification Polyclonal
Conjugate Unconjugated
Description Goat polyclonal antibody raised against synthetic peptide of NFASC.
Dilution Western Blot (0.5-2 ug/mL) The optimal working dilution should be determined by the end user.
Formulation In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Gene NFASC
Gene Alias DKFZp686P2250/FLJ46866/KIAA0756/NF/NRCAML
Gene Symbols NFASC
Host Species Goat
Immunogen A synthetic peptide corresponding to amino acids 877-890 at internal region of human NFASC.
Purification Method Antigen affinity purification
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 23114
Test Specificity This antibody is expected to recognize reported isoforms 1, 2, 3 and 4 (NP_001005388.2;,NP_001153803.1, NP_001153804.1and NP_055905.2 resp).
Target Species Human, Rat
Content And Storage Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
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For Research Use Only

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