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NIPBL Goat anti-Bovine, Dog, Human, Mouse, Orangutan, Rat, Polyclonal Antibody, Abnova™

Catalog No. 89114707 Shop All Abnova Corporation Products
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89-114-707 100 μg
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Catalog No. 89-114-707 Supplier Abnova Corporation Supplier No. PAB10226
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Description

Goat polyclonal antibody raised against synthetic peptide of NIPBL.

This gene encodes the homolog of the Drosophila melanogaster Nipped-B gene product and fungal Scc2-type sister chromatid cohesion proteins. The Drosophila protein facilitates enhancer-promoter communication of remote enhancers and plays a role in developmental regulation. It is also homologous to a family of chromosomal adherins with broad roles in sister chromatid cohesion, chromosome condensation, and DNA repair. The human protein has a bipartite nuclear targeting sequence and a putative HEAT repeat. Condensins, cohesins and other complexes with chromosome-related functions also contain HEAT repeats. Mutations in this gene result in Cornelia de Lange syndrome, a disorder characterized by dysmorphic facial features, growth delay, limb reduction defects, and mental retardation. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq

Specifications

Antigen NIPBL
Applications ELISA, Western Blot
Classification Polyclonal
Conjugate Unconjugated
Description Goat polyclonal antibody raised against synthetic peptide of NIPBL.
Dilution ELISA (1:2000-1:10000) Western Blot (1:500-1:3000) The optimal working dilution should be determined by the end user.
Formulation In 20mM KH2PO4, 150mM NaCl, pH 7.2 (0.01% sodium azide)
Gene NIPBL
Gene Alias CDLS/CDLS1/DKFZp434L1319/FLJ11203/FLJ12597/FLJ13354/FLJ13648/FLJ44854/IDN3/IDN3-B
Gene Symbols NIPBL
Host Species Goat
Immunogen A synthetic peptide corresponding to amino acids 344-356 of human NIPBL.
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 25836
Test Specificity This affinity purified antibody is directed against human IDN3 protein.
Target Species Bovine, Canine, Human, Mouse, Orangutan, Rat
Content And Storage Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
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For Research Use Only

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