NQO1 Goat anti-Dog, Human, Mouse, Polyclonal Antibody, Abnova™

Catalog No.	Quantity
89-132-175	100 μg

Catalog No. 89-132-175 Supplier Abnova Corporation Supplier No. PAB6134

Description

Goat polyclonal antibody raised against synthetic peptide of NQO1.

This gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors and is also associated with Alzheimer's disease (AD). Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq]

Sequence: C-SIPTDNQIKARK

Specifications

• Antigen: NQO1
• Applications: ELISA, Western Blot
• Classification: Polyclonal
• Concentration: 0.5 mg/mL
• Conjugate: Unconjugated
• Description: Goat polyclonal antibody raised against synthetic peptide of NQO1.
• Dilution: ELISA (1:64000) Western Blot (0.03-0.1 ug/mL) The optimal working dilution should be determined by the end user.
• Formulation: In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
• Gene: NQO1
• Gene Alias: DHQU/DIA4/DTD/NMOR1/NMORI/QR1
• Gene Symbols: NQO1
• Host Species: Goat
• Immunogen: A synthetic peptide corresponding to C-terminus of human NQO1.
• Purification Method: Antigen affinity purification
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 1728
• Test Specificity: This products is expected to recognize all three reported isoforms (NP_000894.1, NP_001020604.1 and NP_001020605.1).
• Target Species: Canine, Human, Mouse
• Content And Storage: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid

For Research Use Only