NR1I2, Goat, Polyclonal Antibody, Abnova™

Catalog No.	Quantity
89-115-219	100 μg

Catalog No. 89-115-219 Supplier Abnova Corporation Supplier No. PAB11612

Description

Goat polyclonal antibody raised against synthetic peptide of NR1I2.

This gene product belongs to the nuclear receptor superfamily, members of which are transcription factors characterized by a ligand-binding domain and a DNA-binding domain. The encoded protein is a transcriptional regulator of the cytochrome P450 gene CYP3A4, binding to the response element of the CYP3A4 promoter as a heterodimer with the 9-cis retinoic acid receptor RXR. It is activated by a range of compounds that induce CYP3A4, including dexamethasone and rifampicin. Several alternatively spliced transcripts encoding different isoforms, some of which use non-AUG (CUG) translation initiation codon, have been described for this gene. Additional transcript variants exist, however, they have not been fully characterized. [provided by RefSeq

Sequence: EQFAITLKSYIECNR

Specifications

• Antigen: NR1I2
• Applications: ELISA, Western Blot
• Classification: Polyclonal
• Concentration: 0.5 mg/mL
• Conjugate: Unconjugated
• Description: Goat polyclonal antibody raised against synthetic peptide of NR1I2.
• Dilution: ELISA (1:4000) Western Blot (1-3 ug/mL) The optimal working dilution should be determined by the end user.
• Formulation: In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
• Gene: NR1I2
• Gene Alias: BXR/ONR1/PAR/PAR1/PAR2/PARq/PRR/PXR/SAR/SXR
• Gene Symbols: NR1I2
• Host Species: Goat
• Immunogen: A synthetic peptide corresponding to human NR1I2.
• Purification Method: Antigen affinity purification
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 8856
• Target Species: Human
• Content And Storage: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid

For Research Use Only