NRGN, Goat, Polyclonal Antibody, Abnova™

Goat polyclonal antibody raised against synthetic peptide of NRGN.

Manufacturer:  Abnova Corporation PAB17274

Catalog No. 89-118-939

Description

Neurogranin (NRGN) is the human homolog of the neuron-specific rat RC3/neurogranin gene. This gene encodes a postsynaptic protein kinase substrate that binds calmodulin in the absence of calcium. The NRGN gene contains four exons and three introns. The exons 1 and 2 encode the protein and exons 3 and 4 contain untranslated sequences. It is suggested that the NRGN is a direct target for thyroid hormone in human brain, and that control of expression of this gene could underlay many of the consequences of hypothyroidism on mental states during development as well as in adult subjects. [provided by RefSeq

Sequence: C-KIKSGERGRKG

Specifications

• Antigen: NRGN
• Concentration: 0.5 mg/mL
• Description: Goat polyclonal antibody raised against synthetic peptide of NRGN.
• Formulation: In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
• Format: Liquid
• Gene Symbols: NRGN
• Immunogen: A synthetic peptide corresponding to internal region of human NRGN.
• Quantity: 100 ug
• Storage Requirements: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Monoclonal or Polyclonal: Polyclonal
• Test Specificity: Reported variants represent identical protein: NP_006167.1, NP_001119653.1.

• Applications: ELISA, Immunohistochemistry (PFA fixed), Western Blot
• Conjugate: Unconjugated
• Dilution: ELISA (1:8000) Western Blot (0.1-0.3 ug/mL) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (4-6 ug/mL) The optimal working dilution should be determined by the end user.
• Gene: NRGN
• Gene Alias: RC3|hng
• Host Species: Goat
• Purification Method: Antigen affinity purification
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 4900
• Target Species: Human, Murine, Rat

For Research Use Only