NRGN, Goat, Polyclonal Antibody, Abnova™

Catalog No.	Quantity
89-118-939	100 μg

Catalog No. 89-118-939 Supplier Abnova Corporation Supplier No. PAB17274

Description

Goat polyclonal antibody raised against synthetic peptide of NRGN.

Neurogranin (NRGN) is the human homolog of the neuron-specific rat RC3/neurogranin gene. This gene encodes a postsynaptic protein kinase substrate that binds calmodulin in the absence of calcium. The NRGN gene contains four exons and three introns. The exons 1 and 2 encode the protein and exons 3 and 4 contain untranslated sequences. It is suggested that the NRGN is a direct target for thyroid hormone in human brain, and that control of expression of this gene could underlay many of the consequences of hypothyroidism on mental states during development as well as in adult subjects. [provided by RefSeq

Sequence: C-KIKSGERGRKG

Specifications

• Antigen: NRGN
• Applications: ELISA, Immunohistochemistry (PFA fixed), Western Blot
• Classification: Polyclonal
• Concentration: 0.5 mg/mL
• Conjugate: Unconjugated
• Description: Goat polyclonal antibody raised against synthetic peptide of NRGN.
• Dilution: ELISA (1:8000) Western Blot (0.1-0.3 ug/mL) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (4-6 ug/mL) The optimal working dilution should be determined by the end user.
• Formulation: In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
• Gene: NRGN
• Gene Alias: RC3/hng
• Gene Symbols: NRGN
• Host Species: Goat
• Immunogen: A synthetic peptide corresponding to internal region of human NRGN.
• Purification Method: Antigen affinity purification
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 4900
• Test Specificity: Reported variants represent identical protein: NP_006167.1, NP_001119653.1.
• Target Species: Human, Mouse, Rat
• Content And Storage: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid

For Research Use Only