NUMB, Goat, Polyclonal Antibody, Abnova™

Catalog No.	Quantity
89-132-146	100 μg

Catalog No. 89-132-146 Supplier Abnova Corporation Supplier No. PAB6102

Description

Goat polyclonal antibody raised against synthetic peptide of NUMB.

The protein encoded by this gene plays a role in the determination of cell fates during development. The encoded protein, whose degradation is induced in a proteasome-dependent manner by MDM2, is a membrane-bound protein that has been shown to associate with EPS15, LNX1, and NOTCH1. Four transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq

Sequence: C-PFSSDLQKTFEIEL

Specifications

• Antigen: NUMB
• Applications: ELISA, Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Western Blot
• Classification: Polyclonal
• Concentration: 0.5 mg/mL
• Conjugate: Unconjugated
• Description: Goat polyclonal antibody raised against synthetic peptide of NUMB.
• Dilution: ELISA (1:32000) Western Blot (0.03-0.1 ug/mL) The optimal working dilution should be determined by the end user.
• Formulation: In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
• Gene: NUMB
• Gene Alias: S171
• Gene Symbols: NUMB
• Host Species: Goat
• Immunogen: A synthetic peptide corresponding to C-terminus of human NUMB.
• Purification Method: Antigen affinity purification
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 8650
• Test Specificity: This antibody is expected to recognize all reported isoforms (NP_001005743.1, 001005744.1, NP_0.03735, NP_001005745.1). It is also likely to cross-react with Numblike (NUMBL, GeneID: 9253) which has a very similar C-Terminus, although this has not yet been tested experimentally.
• Target Species: Human, Mouse
• Content And Storage: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid

For Research Use Only