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Description
This gene encodes a multifunctional protein. It has two enzymatically active domains with catalytic activities - peptidylglycine alpha-hydroxylating monooxygenase (PHM) and peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PAL). These catalytic domains work sequentially to catalyze neuroendocrine peptides to active alpha-amidated products. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene but some of their full length sequences are not yet known. [provided by RefSeq
Specifications
Specifications
| Antigen | PAM |
| Applications | ELISA, Western Blot |
| Classification | Polyclonal |
| Concentration | 0.5 mg/mL |
| Conjugate | Unconjugated |
| Description | Goat polyclonal antibody raised against synthetic peptide of PAM. |
| Dilution | ELISA (1:4000) Western Blot (0.3-1 ug/mL) The optimal working dilution should be determined by the end user. |
| Formulation | In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide) |
| Gene | PAM |
| Gene Alias | PAL/PHM |
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