PCBP1 Goat anti-Human, Polyclonal Antibody, Abnova™

Catalog No.	Quantity
89-120-526	100 μg

Catalog No. 89-120-526 Supplier Abnova Corporation Supplier No. PAB18974

Description

Goat polyclonal antibody raised against synthetic peptide of PCBP1.

This intronless gene is thought to have been generated by retrotransposition of a fully processed PCBP-2 mRNA. This gene and PCBP-2 have paralogues (PCBP3 and PCBP4) which are thought to have arisen as a result of duplication events of entire genes. The protein encoded by this gene appears to be multifunctional. It along with PCBP-2 and hnRNPK corresponds to the major cellular poly(rC)-binding protein. It contains three K-homologous (KH) domains which may be involved in RNA binding. This encoded protein together with PCBP-2 also functions as translational coactivators of poliovirus RNA via a sequence-specific interaction with stem-loop IV of the IRES and promote poliovirus RNA replication by binding to its 5'-terminal cloverleaf structure. It has also been implicated in translational control of the 15-lipoxygenase mRNA, human Papillomavirus type 16 L2 mRNA, and hepatitis A virus RNA. The encoded protein is also suggested to play a part in formation of a sequence-specific alpha-globin mRNP complex which is associated with alpha-globin mRNA stability. [provided by RefSeq]

Sequence: C-SIQGQHTISPLD

Specifications

• Antigen: PCBP1
• Applications: ELISA, Western Blot
• Classification: Polyclonal
• Concentration: 0.5 mg/mL
• Conjugate: Unconjugated
• Description: Goat polyclonal antibody raised against synthetic peptide of PCBP1.
• Dilution: ELISA (1:8000) Western Blot (0.1-0.3 ug/mL) The optimal working dilution should be determined by the end user.
• Formulation: In 0.5mg/mL in Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
• Gene: PCBP1
• Gene Alias: HNRPE1/HNRPX/hnRNP-E1/hnRNP-X
• Gene Symbols: PCBP1
• Host Species: Goat
• Immunogen: A synthetic peptide corresponding to amino acids at internal region of human PCBP1.
• Purification Method: Antigen affinity purification
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 5093
• Target Species: Human
• Content And Storage: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid

For Research Use Only