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Description
This gene encodes a proprotein convertase belonging to the proteinase K subfamily of the secretory subtilase family. The encoded protein is synthesized as a soluble zymogen that undergoes autocatalytic intramolecular processing in the endoplasmic reticulum. The protein may function as a proprotein convertase. This protein plays a role in cholesterol homeostasis and may have a role in the differentiation of cortical neurons. Mutations in this gene have been associated with a third form of autosomal dominant familial hypercholesterolemia (HCHOLA3). [provided by RefSeq
Specifications
Specifications
| Antigen | PCSK9 |
| Applications | ELISA, Western Blot |
| Classification | Polyclonal |
| Concentration | 0.5 mg/mL |
| Conjugate | Unconjugated |
| Description | Goat polyclonal antibody raised against synthetic peptide of PCSK9. |
| Dilution | ELISA (1:32000) Western Blot (0.1-0.5 ug/mL) The optimal working dilution should be determined by the end user. |
| Formulation | In 0.5mg/mL in Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide) |
| Gene | PCSK9 |
| Gene Alias | FH3/HCHOLA3/LDLCQ1/NARC-1/NARC1 |
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