PLN, Goat, Polyclonal Antibody, Abnova™

Catalog No.	Quantity
89-120-592	100 μg

Catalog No. 89-120-592 Supplier Abnova Corporation Supplier No. PAB19037

Description

Goat polyclonal antibody raised against synthetic peptide of PLN.

The protein encoded by this gene is found as a pentamer and is a major substrate for the cAMP-dependent protein kinase in cardiac muscle. The encoded protein is an inhibitor of cardiac muscle sarcoplasmic reticulum Ca(2+)-ATPase in the unphosphorylated state, but inhibition is relieved upon phosphorylation of the protein. The subsequent activation of the Ca(2+) pump leads to enhanced muscle relaxation rates, thereby contributing to the inotropic response elicited in heart by beta-agonists. The encoded protein is a key regulator of cardiac diastolic function. Mutations in this gene are a cause of inherited human dilated cardiomyopathy with refractory congestive heart failure. [provided by RefSeq]

Sequence: KVQYLTRSAIRR-C

Specifications

• Antigen: PLN
• Applications: ELISA, Western Blot
• Classification: Polyclonal
• Concentration: 0.5 mg/mL
• Conjugate: Unconjugated
• Description: Goat polyclonal antibody raised against synthetic peptide of PLN.
• Dilution: ELISA (1:8000) Western Blot (0.01-0.03 ug/mL) The optimal working dilution should be determined by the end user.
• Formulation: In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
• Gene: PLN
• Gene Alias: CMD1P/PLB
• Gene Symbols: PLN
• Host Species: Goat
• Immunogen: A synthetic peptide corresponding to amino acids at N-terminus of human PLN.
• Purification Method: Antigen affinity purification
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 5350
• Target Species: Human, Rat
• Content And Storage: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid

For Research Use Only